TTR Antikörper (AA 71-98)

Produktnummer ABIN7876613

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TTR in WB, IF, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TTR Antikörper (AA 71-98) (ABIN7876613)

Target: TTR (Transthyretin (TTR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TTR Antikörper

Bindungsspezifität: AA 71-98

Verwendungszweck: Transthyretin Antibody / TTR / Prealbumin

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 71-98 from the human protein was used as the immunogen for the Transthyretin antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Transthyretin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Transthyretin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: Transthyretin

Hintergrund: Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

UniProt: P02766

Pathways: Hormone Transport