PRELP Antikörper (AA 69-353)

Produktnummer ABIN7876441

Der Kaninchen Polyklonal anti-PRELP Antikörper (ABIN7876441) detektiert spezifisch PRELP in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PRELP Antikörper (AA 69-353) (ABIN7876441)

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRELP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PRELP Antikörper

Bindungsspezifität: AA 69-353

Verwendungszweck: Prolargin Antibody / PRELP

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids I69-R353) was used as the immunogen for the Prolargin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Prolargin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Prolargin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PRELP

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Andere Bezeichnung: Prolargin

Hintergrund: Prolargin is a protein that in humans is encoded by the PRELP gene. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

UniProt: P51888

Pathways: Glycosaminoglycan Metabolic Process