CDK14 Antikörper (AA 67-96)

Produktnummer ABIN7876387

Der Kaninchen Polyklonal anti-CDK14 Antikörper (ABIN7876387) detektiert spezifisch CDK14 in WB, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CDK14 Antikörper (AA 67-96) (ABIN7876387)

Target: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CDK14 Antikörper

Bindungsspezifität: AA 67-96

Verwendungszweck: CDK14 Antibody / Cyclin-dependent kinase 14 / PFTAIRE-1

Aufreinigung: SAS precipitation

Immunogen: A portion of amino acids 67-96 from the human protein was used as the immunogen for the CDK14 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the CDK14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CDK14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CDK14

Target: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Andere Bezeichnung: CDK14

Hintergrund: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. [UniProt]

UniProt: O94921