Gasdermin A Antikörper (AA 66-94)

Produktnummer ABIN7876353

Der Kaninchen Polyklonal anti-Gasdermin A Antikörper wird verwendet zum Nachweis von Gasdermin A in Proben von Human und Maus. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für Gasdermin A Antikörper (AA 66-94) (ABIN7876353)

Target: Gasdermin A (GSDMA)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gasdermin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Gasdermin A Antikörper

Bindungsspezifität: AA 66-94

Verwendungszweck: GSDMA Antibody / Gasdermin-A

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 66-94 from the human protein was used as the immunogen for this GSDMA antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the GSDMA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4oC for up to one month. For long term, aliquot the GSDMA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Gasdermin A

Target: Gasdermin A (GSDMA)

Andere Bezeichnung: GSDMA

Hintergrund: Gasdermin-A is a protein that plays a crucial role in programmed cell death, or pyroptosis, a process that is essential for the body to eliminate infected or damaged cells. This protein acts as a pore-forming molecule, causing the cell membrane to rupture and release pro-inflammatory molecules that signal the immune system to clear away the debris. Recent studies have shown that dysregulation of Gasdermin-A can lead to a variety of health issues, including autoimmune diseases, inflammatory disorders, and even cancer.

UniProt: Q96QA5