Der Kaninchen Polyklonal anti-MVD Antikörper (ABIN7876162) detektiert spezifisch MVD in WB, ELISA, IHC (p) und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
MVD
Reaktivität: Maus, Ratte
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the Diphosphomevalonate decarboxylase antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the Diphosphomevalonate decarboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
MVD
(Mevalonate (Diphospho) Decarboxylase (MVD))
Andere Bezeichnung
Diphosphomevalonate decarboxylase
Hintergrund
The enzyme mevalonate pyrophosphate decarboxylase (MVD, EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVD sequence.