RHBDD1 Antikörper (AA 62-293)

Produktnummer ABIN7876156

Der Kaninchen Polyklonal anti-RHBDD1 Antikörper (ABIN7876156) detektiert spezifisch RHBDD1 in WB, ELISA, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RHBDD1 Antikörper (AA 62-293) (ABIN7876156)

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHBDD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RHBDD1 Antikörper

Bindungsspezifität: AA 62-293

Verwendungszweck: RRP4 Antibody / EXOSC2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R62-G293) was used as the immunogen for the RRP4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RRP4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the RRP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RHBDD1

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Andere Bezeichnung: RRP4

Hintergrund: Exosome component 2, also known as Exosome complex component RRP4 and EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events.

UniProt: Q13868