HHEX Antikörper (AA 60-228)

Produktnummer ABIN7875990

Der Kaninchen Polyklonal anti-HHEX Antikörper wird verwendet zum Nachweis von HHEX in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für HHEX Antikörper (AA 60-228) (ABIN7875990)

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HHEX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HHEX Antikörper

Bindungsspezifität: AA 60-228

Verwendungszweck: Zebrafish Hhex Antibody / Hex / Hematopoietically expressed homeobox protein

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Hhex recombinant protein (amino acids Y60-L228) was used as the immunogen for the Zebrafish Hhex antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Hhex antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Hhex antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HHEX

Target: HHEX (Hematopoietically Expressed Homeobox (HHEX))

Andere Bezeichnung: Hhex

Hintergrund: Hhex, or hematopoietically expressed homeobox, is a transcription factor that plays a critical role in early embryonic development, especially in the formation of the forebrain, thyroid, liver, and pancreas. In zebrafish, Hhex is essential for the specification and differentiation of endodermal and anterior mesodermal tissues.

Hhex is expressed early in the developing embryo, particularly in regions that give rise to the anterior foregut and associated organs. It regulates the expression of key developmental genes involved in organogenesis and is required for proper morphogenesis of the thyroid gland and liver. In the developing brain, Hhex also contributes to the patterning of forebrain structures.

Loss of Hhex function in zebrafish leads to defects in anterior endoderm formation, impaired thyroid and liver development, and abnormalities in forebrain organization. Because of its conserved function in vertebrate development, zebrafish Hhex serves as a valuable model for understanding congenital organ defects, endodermal lineage specification, and early tissue patterning.

Zebrafish Hhex is widely used in developmental biology, stem cell research, and disease modeling, particularly in studies focused on endocrine and hepatic organ development.

UniProt: Q9IAV3