Der Kaninchen Polyklonal anti-Calretinin Antikörper wird verwendet zum Nachweis von Calretinin in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC (p), IF und FACS.
Optimal dilution of the Calbindin 2 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the Calbindin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
Calretinin (CALB2)
(Calbindin 2 (CALB2))
Andere Bezeichnung
Calbindin 2
Hintergrund
Calretinin, also known as calbindin 2 (formerly 29 kDa calbindin), is a calcium-binding protein involved in calcium signaling. In humans, the calretinin protein is encoded by the CALB2 gene. It is mapped to 16q22.2. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.