Septin 9 Antikörper (AA 57-85)

Produktnummer ABIN7875816

Der Kaninchen Polyklonal anti-Septin 9 Antikörper wird verwendet zum Nachweis von Septin 9 in Proben von Human. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für Septin 9 Antikörper (AA 57-85) (ABIN7875816)

Target: Septin 9 (SEPT9)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Septin 9 Antikörper

Bindungsspezifität: AA 57-85

Verwendungszweck: Septin 9 Antibody / SEPT9

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 57-85 from the human protein were used as the immunogen for the Septin 9 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Septin 9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Septin 9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Septin 9

Target: Septin 9 (SEPT9)

Andere Bezeichnung: Septin 9

Hintergrund: The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.

UniProt: Q9UHD8