DRD4 Antikörper (AA 57-387)

Produktnummer ABIN7875806

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DRD4 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für DRD4 Antikörper (AA 57-387) (ABIN7875806)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-DRD4 Antikörper

Bindungsspezifität: AA 57-387

Verwendungszweck: Drd4 Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant mouse protein (amino acids A57-C387) was used as the immunogen for the Drd4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Drd4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Drd4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Andere Bezeichnung: Drd4

Hintergrund: D(4) dopamine receptor is aproteinthat in humans is encoded by the Drd4gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P51436

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity