Emerin Antikörper (AA 56-167)

Produktnummer ABIN7875759

Der Maus Monoklonal anti-Emerin Antikörper wird verwendet zum Nachweis von Emerin in Proben von Human. Er wurde validiert für WB, IF und IHC (p).

Kurzübersicht für Emerin Antikörper (AA 56-167) (ABIN7875759)

Target: Emerin (EMD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Emerin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: EMD-2167

Produktdetails anti-Emerin Antikörper

Bindungsspezifität: AA 56-167

Verwendungszweck: Emerin Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 56-167 from the human protein was used as the immunogen for the Emerin antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Titering of the Emerin antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Emerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Emerin

Target: Emerin (EMD)

Andere Bezeichnung: Emerin

Hintergrund: Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.

UniProt: P50402