SNRNP200 Antikörper (AA 557-2129)

Produktnummer ABIN7875725

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SNRNP200 in WB, ELISA, IF, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SNRNP200 Antikörper (AA 557-2129) (ABIN7875725)

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRNP200 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SNRNP200 Antikörper

Bindungsspezifität: AA 557-2129

Verwendungszweck: SNRNP200 Antibody / U5 snRNP-specific 200 kDa protein

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K557-A2129) was used as the immunogen for the SNRNP200 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SNRNP200 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SNRNP200 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SNRNP200

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Andere Bezeichnung: SNRNP200

Hintergrund: U5 small nuclear ribonucleoprotein 200 kDa helicase is an enzyme that in humans is encoded by the SNRNP200 gene. Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization