THBD
Reaktivität: Human
WB, FACS, IF
Wirt: Kaninchen
Polyclonal
RB56919
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting points. Titration of the Thrombomodulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Thrombomodulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
Thrombomodulin (THBD)
Andere Bezeichnung
Thrombomodulin
Hintergrund
Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]