ORMDL3 Antikörper (AA 53-81)

Produktnummer ABIN7875600

Der Kaninchen Polyklonal anti-ORMDL3 Antikörper wird verwendet zum Nachweis von ORMDL3 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für ORMDL3 Antikörper (AA 53-81) (ABIN7875600)

Target: ORMDL3 (ORM1-Like 3 (ORMDL3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORMDL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ORMDL3 Antikörper

Bindungsspezifität: AA 53-81

Verwendungszweck: ORMDL3 Antibody / ORM1-like protein 3

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 53-81 from the human protein was used as the immunogen for the ORMDL3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the ORMDL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ORMDL3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ORMDL3

Target: ORMDL3 (ORM1-Like 3 (ORMDL3))

Andere Bezeichnung: ORMDL3

Hintergrund: ORM1-like protein 3 is a protein that is encoded by the ORMDL3 gene. It belongs to a family of proteins known as ORM proteins, which play a crucial role in regulating the levels of sphingolipids - a class of lipids that are involved in various cellular processes. In particular, ORMDL3 has been shown to be a key player in the regulation of sphingolipid synthesis, and aberrant expression of this protein has been implicated in a number of diseases, including asthma. Recent studies have revealed that ORMDL3 plays a critical role in the development of asthma. It has been shown that individuals with certain genetic variations that result in increased ORMDL3 expression are at a higher risk of developing asthma. Additionally, ORMDL3 has been shown to be involved in the regulation of immune responses in the lungs, with increased levels of this protein leading to inflammation and airway hyperreactivity - hallmark features of asthma.

UniProt: Q8N138