Netrin 3 Antikörper (AA 51-473)

Produktnummer ABIN7875521

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Netrin 3 in WB, ELISA, IHC (p) und IF. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Netrin 3 Antikörper (AA 51-473) (ABIN7875521)

Target: Netrin 3 (Ntn3)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Netrin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-Netrin 3 Antikörper

Bindungsspezifität: AA 51-473

Verwendungszweck: NTN3 Antibody / Netrin 3

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (R51-R473) was used as the immunogen for the NTN3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NTN3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NTN3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Netrin 3

Target: Netrin 3 (Ntn3)

Andere Bezeichnung: NTN3

Hintergrund: Netrins are a family of highly conserved proteins responsible for axon guidance and cell movement throughout neural development. Netrins can be divided into secreted netrins (netrin 1,3,4 and 5) and membrane-tethered glycophosphatidylinositol (GPI)-linked netrins (netrin G1 and G2). Secreted netrins carry their function via interaction with several receptors that include the deleted in colorectal (DCC) family, and the uncoordinated-5 (UNC5-A through UNC5-D) family. Netrin-3 was discovered in 1997 using sequence homology searching of netrin-2. Similarly to other netrins, Netrin-3 plays an important role in the development of the nervous system. Netrin-3 structure consist of a laminin-like domain located on the N-terminal, three epidermal growth factors like repeats (EGF), and a C-terminal netrin-like domain (NTR). Mutations in NTN3, the gene encoding netrin-3 was found to be associated with the development of several carcinomas.

UniProt: O00634

Pathways: Regulation of Muscle Cell Differentiation