ANAPC2 Antikörper (AA 51-272)

Produktnummer ABIN7875516

Der Kaninchen Polyklonal anti-ANAPC2 Antikörper wird verwendet zum Nachweis von ANAPC2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF, FACS und IHC (p).

Kurzübersicht für ANAPC2 Antikörper (AA 51-272) (ABIN7875516)

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ANAPC2 Antikörper

Bindungsspezifität: AA 51-272

Verwendungszweck: ANAPC2 Antibody / APC2

Aufreinigung: Affinity purified

Immunogen: A human recombinant partial protein (amino acids K51-R272) was used as the immunogen for the ANAPC2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ANAPC2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ANAPC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ANAPC2

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Andere Bezeichnung: ANAPC2

Hintergrund: Anaphase-promoting complex subunit 2 is an enzyme that in humans is encoded by the ANAPC2 gene. A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

UniProt: Q9UJX6

Pathways: Regulation of Cell Size