Der Kaninchen Polyklonal anti-ALDOA Antikörper wird verwendet zum Nachweis von ALDOA in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, FACS und IHC (p).
ALDOA
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
2E6
unconjugated
Applikationshinweise
Optimal dilution of the Aldolase A antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the Aldolase A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
ALDOA
(Aldolase A, Fructose-Bisphosphate (ALDOA))
Andere Bezeichnung
Aldolase A
Hintergrund
Aldolase A (ALDOA, or ALDA), also known as fructose-bisphosphate aldolase, is an enzyme that in humans is encoded by the ALDOA gene on chromosome 16. This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.