CEACAM1 Antikörper (AA 50-250)

Produktnummer ABIN7875347

Dieser Maus Monoklonal Antikörper detektiert spezifisch CEACAM1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CEACAM1 Antikörper (AA 50-250) (ABIN7875347)

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CEACAM1-4840

Produktdetails anti-CEACAM1 Antikörper

Bindungsspezifität: AA 50-250

Verwendungszweck: CEACAM1 Antibody / Biliary glycoprotein 1 / BGP-1

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the CEACAM1 antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CEACAM1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CEACAM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Andere Bezeichnung: CEACAM1

Hintergrund: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM1, also called Biliary glycoprotein 1 (BGP-1), is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue three dimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is under-expressed in colorectal cancers, suggesting a role in tumor suppression.

UniProt: P13688