TNK2 Antikörper (AA 491-1038)

Produktnummer ABIN7875263

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TNK2 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TNK2 Antikörper (AA 491-1038) (ABIN7875263)

Target: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TNK2 Antikörper

Bindungsspezifität: AA 491-1038

Verwendungszweck: Activated CDC42 kinase 1 Antibody / ACK1

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M491-R1038) was used as the immunogen for the Activated CDC42 kinase 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Activated CDC42 kinase 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Activated CDC42 kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TNK2

Target: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Andere Bezeichnung: Activated CDC42 kinase 1

Hintergrund: Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

UniProt: Q07912