ITK Antikörper (AA 49-465)

Produktnummer ABIN7875257

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ITK in WB, ELISA, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ITK Antikörper (AA 49-465) (ABIN7875257)

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ITK Antikörper

Bindungsspezifität: AA 49-465

Verwendungszweck: IL2-inducible T-cell kinase Antibody / ITK

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R49-F465) was used as the immunogen for the IL2-inducible T-cell kinase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL2-inducible T-cell kinase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IL2-inducible T-cell kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ITK

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Andere Bezeichnung: IL2-inducible T-cell kinase

Hintergrund: Tyrosine-protein kinase ITK/TSK, also known as interleukin-2-inducible T-cell kinase or simply ITK, is a protein that in humans is encoded by the ITK gene. It is a member of the TEC family of kinases. This gene is mapped to 5q33.3. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein is thought to play a role in T-cell proliferation and differentiation. Furthermore, ITK is functionally important for the development and effector function of Th2 and Th17 cells.

UniProt: Q08881

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung