Mps1 Antikörper (AA 487-821)

Produktnummer ABIN7875232

Der Kaninchen Polyklonal anti-Mps1 Antikörper (ABIN7875232) detektiert spezifisch Mps1 in WB, ELISA, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Mps1 Antikörper (AA 487-821) (ABIN7875232)

Target: Mps1 (TTK)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mps1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-Mps1 Antikörper

Bindungsspezifität: AA 487-821

Verwendungszweck: TTK Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids Q487-S821) was used as the immunogen for the TTK antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TTK antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the TTK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Mps1

Target: Mps1 (TTK)

Andere Bezeichnung: TTK

Hintergrund: Dual specificity protein kinase TTK is a protein that in humans is encoded by the TTK gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

UniProt: P33981