MAPK8IP1 Antikörper (AA 470-498)

Produktnummer ABIN7875168

Der Kaninchen Polyklonal anti-MAPK8IP1 Antikörper wird verwendet zum Nachweis von MAPK8IP1 in Proben von Human. Er wurde validiert für WB, IF, IHC (p) und FACS.

Kurzübersicht für MAPK8IP1 Antikörper (AA 470-498) (ABIN7875168)

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK8IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-MAPK8IP1 Antikörper

Bindungsspezifität: AA 470-498

Verwendungszweck: MAPK8IP1 Antibody / JIP1

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 470-498 from the human protein was used as the immunogen for the MAPK8IP1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the MAPK8IP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MAPK8IP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MAPK8IP1

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Andere Bezeichnung: MAPK8IP1

Hintergrund: JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

UniProt: Q9UQF2