Dynamin 1-Like Antikörper (AA 452-736)

Produktnummer ABIN7875098

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Dynamin 1-Like in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Dynamin 1-Like Antikörper (AA 452-736) (ABIN7875098)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Dynamin 1-Like Antikörper

Bindungsspezifität: AA 452-736

Verwendungszweck: Dynamin-1-like protein Antibody / DNM1L / DRP1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q452-W736) was used as the immunogen for the Dynamin-1-like protein antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Dynamin-1-like protein antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Dynamin-1-like protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: Dynamin-1-like protein

Hintergrund: Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O00429