SMOX Antikörper (AA 45-454)

Produktnummer ABIN7875072

Der Kaninchen Polyklonal anti-SMOX Antikörper wird verwendet zum Nachweis von SMOX in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, WB, IF, FACS und IHC (p).

Kurzübersicht für SMOX Antikörper (AA 45-454) (ABIN7875072)

Target: SMOX (Spermine Oxidase (SMOX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMOX Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SMOX Antikörper

Bindungsspezifität: AA 45-454

Verwendungszweck: PAO-1 Antibody / Polyamine oxidase 1 / SMOX

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E45-Q454) was used as the immunogen for the PAO-1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PAO-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PAO-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SMOX

Target: SMOX (Spermine Oxidase (SMOX))

Andere Bezeichnung: PAO-1

Hintergrund: Spermine oxidase, also called Polyamine oxidase 1 (PAO-1), is an enzyme that in humans is encoded by the SMOX gene. Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.

UniProt: Q9NWM0