CLPB Antikörper (AA 438-707)

Produktnummer ABIN7875000

Der Kaninchen Polyklonal anti-CLPB Antikörper wird verwendet zum Nachweis von CLPB in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC (p), FACS und IF.

Kurzübersicht für CLPB Antikörper (AA 438-707) (ABIN7875000)

Target: CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-CLPB Antikörper

Bindungsspezifität: AA 438-707

Verwendungszweck: CLPB Antibody / Caseinolytic peptidase B protein

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids Q438-I707) was used as the immunogen for the CLPB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CLPB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CLPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CLPB

Target: CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

Andere Bezeichnung: CLPB

Hintergrund: This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants.

UniProt: Q9H078