M6PR Antikörper (AA 424-529)

Produktnummer ABIN7874936

Dieser Maus Monoklonal Antikörper detektiert spezifisch M6PR in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für M6PR Antikörper (AA 424-529) (ABIN7874936)

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser M6PR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 6G2

Produktdetails anti-M6PR Antikörper

Bindungsspezifität: AA 424-529

Verwendungszweck: M6PR Antibody / IGF2R

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the M6PR antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the M6PR antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the M6PR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Andere Bezeichnung: M6PR

Hintergrund: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

UniProt: P11717