IGF2R Antikörper (AA 424-529)

Produktnummer ABIN7874935

Der Maus Monoklonal anti-IGF2R Antikörper (Klon 4I11) (ABIN7874935) detektiert spezifisch IGF2R in WB, FACS, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IGF2R Antikörper (AA 424-529) (ABIN7874935)

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 4I11

Produktdetails anti-IGF2R Antikörper

Bindungsspezifität: AA 424-529

Verwendungszweck: IGF2R Antibody / M6PR

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the IGF2R antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IGF2R antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IGF2R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Andere Bezeichnung: IGF2R

Hintergrund: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

UniProt: P11717