HSD17B8 Antikörper (AA 42-244)

Produktnummer ABIN7874918

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HSD17B8 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für HSD17B8 Antikörper (AA 42-244) (ABIN7874918)

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-HSD17B8 Antikörper

Bindungsspezifität: AA 42-244

Verwendungszweck: HSD17B8 Antibody / 17-beta-hydroxysteroid dehydrogenase 8

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D42-D244) was used as the immunogen for the HSD17B8 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HSD17B8 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the HSD17B8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HSD17B8

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Andere Bezeichnung: HSD17B8

Hintergrund: Estradiol 17 beta-dehydrogenase 8, also called 17-beta-HSD 8 and Protein Ke6, is an enzyme that in humans is encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

UniProt: Q92506

Pathways: Steroid Hormone Biosynthesis