Syncytin A (SYNA) (AA 400-429) Antikörper

Produktnummer ABIN7874713

Der Kaninchen Polyklonal anti-Syncytin A Antikörper (ABIN7874713) detektiert spezifisch Syncytin A in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Syncytin A (SYNA) (AA 400-429) Antikörper (ABIN7874713)

Target: Syncytin A (SYNA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 400-429

Verwendungszweck: Syncytin 1 Antibody / ERVW-1

Immunogen: A portion of amino acids 400-429 from the human protein was used as the immunogen for this Syncytin 1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Syncytin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Syncytin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: Syncytin A (SYNA)

Andere Bezeichnung: Syncytin 1

Hintergrund: Syncytin 1 is a protein encoded by the ERVW-1 gene, which belongs to the human endogenous retrovirus W family. Endogenous retroviruses are remnants of ancient viral infections that have inserted their genetic material into the human genome. These genetic elements have been preserved through generations and have been co-opted by our bodies for various functions. One of the most intriguing functions of Syncytin 1 is its role in placental development. During pregnancy, Syncytin 1 is expressed in the trophoblast cells of the placenta, where it helps in the formation of syncytia - multinucleated cells that facilitate nutrient exchange between the mother and the growing fetus. This process is essential for the successful progression of pregnancy and the health of both the mother and the baby. Recent research has pointed to its involvement in various physiological processes, including immune modulation and tissue repair. Its expression has been detected in the brain, where it may play a role in neuroprotection and synaptic plasticity.

UniProt: Q9UQF0