SMOX Antikörper (AA 40-555)

Produktnummer ABIN7874706

Der Kaninchen Polyklonal anti-SMOX Antikörper wird verwendet zum Nachweis von SMOX in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und WB.

Kurzübersicht für SMOX Antikörper (AA 40-555) (ABIN7874706)

Target: SMOX (Spermine Oxidase (SMOX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMOX Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-SMOX Antikörper

Bindungsspezifität: AA 40-555

Verwendungszweck: SMOX Antibody / Spermine oxidase / PAO-1

Aufreinigung: Affinity purified

Immunogen: A mouse recombinant protein (amino acids A40-P555) was used as the immunogen for the SMOX antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SMOX antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SMOX antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SMOX

Target: SMOX (Spermine Oxidase (SMOX))

Andere Bezeichnung: SMOX

Hintergrund: Spermine oxidase is an enzyme that in humans is encoded by the SMOX gene. It is mapped to 2, 2 F1. Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.

UniProt: Q99K82