MADD Antikörper (AA 4-335)

Produktnummer ABIN7874673

Der Kaninchen Polyklonal anti-MADD Antikörper wird verwendet zum Nachweis von MADD in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für MADD Antikörper (AA 4-335) (ABIN7874673)

Target: MADD (MAP-Kinase Activating Death Domain (MADD))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MADD Antikörper

Bindungsspezifität: AA 4-335

Verwendungszweck: Zebrafish Madd Antibody / MAP kinase-activating death domain protein

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Madd recombinant protein (amino acids K4-Y335) was used as the immunogen for the Zebrafish Madd antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Madd antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Madd antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MADD

Target: MADD (MAP-Kinase Activating Death Domain (MADD))

Andere Bezeichnung: Madd

Hintergrund: MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

Pathways: Caspase Kaskade in der Apoptose