FLNB Antikörper (AA 397-701)

Produktnummer ABIN7874650

Der Maus Monoklonal anti-FLNB Antikörper (Klon 11E2D2) (ABIN7874650) detektiert spezifisch FLNB in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FLNB Antikörper (AA 397-701) (ABIN7874650)

Target: FLNB (Filamin B, beta (FLNB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FLNB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 11E2D2

Produktdetails anti-FLNB Antikörper

Bindungsspezifität: AA 397-701

Verwendungszweck: Filamin B Antibody / Migfilin-1 / FLNB / FBLIM1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids Q397-D701) was used as the immunogen for the Filamin B antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Filamin B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Filamin B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu FLNB

Target: FLNB (Filamin B, beta (FLNB))

Andere Bezeichnung: Filamin B

Hintergrund: Filamin B, beta (FLNB), also known as Filamin B (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

UniProt: O75369

Pathways: Maintenance of Protein Location