STAR Antikörper (AA 39-108)

Produktnummer ABIN7874562

Der Maus Monoklonal anti-STAR Antikörper wird verwendet zum Nachweis von STAR in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für STAR Antikörper (AA 39-108) (ABIN7874562)

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser STAR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: STAR-3976

Produktdetails anti-STAR Antikörper

Bindungsspezifität: AA 39-108

Verwendungszweck: StAR Antibody / Steroidogenic acute regulatory protein

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 39-108) from the human protein was used as the immunogen for the StAR antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the StAR antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the StAR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu STAR

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Andere Bezeichnung: StAR

Hintergrund: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

UniProt: P49675

Pathways: Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis