STAR Antikörper (AA 39-108)

Produktnummer ABIN7874561

Dieser Maus Monoklonal Antikörper detektiert spezifisch STAR in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STAR Antikörper (AA 39-108) (ABIN7874561)

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser STAR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: STAR-3976

Produktdetails anti-STAR Antikörper

Bindungsspezifität: AA 39-108

Verwendungszweck: StAR Antibody / Steroidogenic acute regulatory protein (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 39-108) from the human protein was used as the immunogen for the StAR antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the StAR antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the StAR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu STAR

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Andere Bezeichnung: StAR

Hintergrund: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

UniProt: P49675

Pathways: Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis