AKAP12 Antikörper (AA 387-1620)

Produktnummer ABIN7874549

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AKAP12 in WB, ELISA, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für AKAP12 Antikörper (AA 387-1620) (ABIN7874549)

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-AKAP12 Antikörper

Bindungsspezifität: AA 387-1620

Verwendungszweck: AKAP12 Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant mouse protein (amino acids E387-H1620) was used as the immunogen for the AKAP12 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the AKAP12 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the AKAP12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu AKAP12

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Andere Bezeichnung: AKAP12

Hintergrund: A-kinase anchor protein 12, also called AKAP250, is an enzyme that in humans is encoded by the AKAP12 gene. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinase A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

UniProt: Q9WTQ5

Pathways: cAMP Metabolic Process