Myosin VI Antikörper (AA 383-786)

Produktnummer ABIN7874533

Der Kaninchen Polyklonal anti-Myosin VI Antikörper (ABIN7874533) detektiert spezifisch Myosin VI in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Myosin VI Antikörper (AA 383-786) (ABIN7874533)

Target: Myosin VI (MYO6)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin VI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-Myosin VI Antikörper

Bindungsspezifität: AA 383-786

Verwendungszweck: MYO6 Antibody / Unconventional Myosin-6

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (Q383-H786) was used as the immunogen for the MYO6 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MYO6 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MYO6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Myosin VI

Target: Myosin VI (MYO6)

Andere Bezeichnung: MYO6

Hintergrund: Unconventional myosin-VI, is a protein that in humans is coded for by MYO6. This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization