MNT Antikörper (AA 381-564)
Kurzübersicht für MNT Antikörper (AA 381-564) (ABIN7874523)
Target
Alle MNT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 381-564
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Verwendungszweck
- MNT Antibody
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Aufreinigung
- Affinity purified
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Immunogen
- Recombinant human protein (amino acids H381-N564) was used as the immunogen for the MNT antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the MNT antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the MNT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MNT (MNT, MAX Dimerization Protein (MNT))
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Andere Bezeichnung
- MNT
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Hintergrund
- MNT (Max's Next Tango) is a Max-binding protein that is encoded by the MNT gene. It is mapped to 17p13.3. The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
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UniProt
- Q99583
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Pathways
- Chromatin Binding, Regulation of Muscle Cell Differentiation
Target
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