Glutathione Reductase Antikörper (AA 380-408)
Kurzübersicht für Glutathione Reductase Antikörper (AA 380-408) (ABIN7874518)
Target
Alle Glutathione Reductase (GSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 380-408
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Verwendungszweck
- GSR Antibody / Glutathione Reductase
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 380-408 from the human protein was used as the immunogen for the GSR antibody.
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Isotyp
- IgG
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the GSR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the GSR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Glutathione Reductase (GSR)
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Andere Bezeichnung
- GSR
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Hintergrund
- This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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UniProt
- P00390
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Pathways
- Thyroid Hormone Synthesis, Cell RedoxHomeostasis
Target
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