FTL Antikörper (AA 38-165) (Biotin)
Kurzübersicht für FTL Antikörper (AA 38-165) (Biotin) (ABIN7874494)
Target
Alle FTL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 38-165
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Verwendungszweck
- FTL Antibody / Biotin Conjugate
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A portion of amino acids 38-165 from the human protein was used as the immunogen for the FTL antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the FTL antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the FTL antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
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- FTL (Ferritin, Light Polypeptide (FTL))
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Andere Bezeichnung
- FTL
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Hintergrund
- Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
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UniProt
- P02792
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Pathways
- Transition Metal Ion Homeostasis
Target
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