Desmoglein 3 Antikörper (AA 379-491)
Kurzübersicht für Desmoglein 3 Antikörper (AA 379-491) (ABIN7874484)
Target
Alle Desmoglein 3 (DSG3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 379-491
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Verwendungszweck
- Desmoglein 3 Antibody / DSG3 (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A recombinant human partial protein (amino acids 379-491) was used as the immunogen for the Desmoglein 3 antibody.
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Isotyp
- IgG1, kappa
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human IHC Wirt: Maus Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human IHC Wirt: Maus Monoclonal 543M unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human IHC, ICC Wirt: Maus Monoclonal BC11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
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Applikationshinweise
- Optimal dilution of the Desmoglein 3 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Desmoglein 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Desmoglein 3 (DSG3)
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Andere Bezeichnung
- Desmoglein 3
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Hintergrund
- Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
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UniProt
- P32926
Target
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