ZNF202 Antikörper (AA 37-132)

Produktnummer ABIN7874390

Dieser Maus Monoklonal Antikörper detektiert spezifisch ZNF202 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ZNF202 Antikörper (AA 37-132) (ABIN7874390)

Target: ZNF202 (Zinc Finger Protein 202 (ZNF202))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZNF202 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-ZNF202-1C4

Produktdetails anti-ZNF202 Antikörper

Bindungsspezifität: AA 37-132

Verwendungszweck: ZNF202 Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 37-132) from the human protein was used as the immunogen for the ZNF202 antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ZNF202 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ZNF202 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ZNF202

Target: ZNF202 (Zinc Finger Protein 202 (ZNF202))

Andere Bezeichnung: ZNF202

Hintergrund: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF202 (zinc finger protein 202), also known as ZKSCAN10, is a 648 amino acid protein that contains eight C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. Localized to the nucleus and expressed at high levels in the testis, ZNF202 belongs to the Kruppel C2H2-type zincfinger protein family and functions as a transcriptional repressor of genes that are involved in lipid metabolism. ZNF202 regulates the expression of several classes of proteins, including lipoprotein particles, transporters involved in lipid homeostasis, enzymes involved in lipid processing and a wide variety of proteins that are associated with energy metabolism. Defects in the gene encoding ZNF202 are associated with high cholesterol and may be involved in the pathogenesis of lung, ovarian and breast cancer. Two isoforms of ZNF202, designated a and b, exist due to alternative splicing events

UniProt: O95125