Der Maus Monoklonal anti-ZSCAN12 Antikörper (Klon PCRP-ZSCAN12-2B2) (ABIN7874389) detektiert spezifisch ZSCAN12 in IF und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
ZSCAN12
Reaktivität: Human
IF, FACS
Wirt: Maus
Monoclonal
PCRP-ZSCAN12-2B2
unconjugated
Applikationshinweise
Optimal dilution of the ZSCAN12 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the ZSCAN12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
ZSCAN12
(Zinc Finger and SCAN Domain Containing 12 (ZSCAN12))
Andere Bezeichnung
ZSCAN12
Hintergrund
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Belonging to the Kruppel C2H2-type zinc-finger protein family, ZFP96 (zinc finger protein 96 homolog), also known as ZSCAN12 (zinc finger and SCAN domain-containing protein 12) and zinc finger protein 305, is a 604 amino acid nuclear protein that contains one SCAN box domain and 11 C2H2-type zinc fingers. ZFP96 is upregulated by 8-fold from day 13 of pregnancy to day 1 post-partum, suggesting that ZFP96 functions as a transcription factor by switching off pro-survival genes and/or upregulating pro-apoptotic genes of the corpus luteum.