Der Kaninchen Polyklonal anti-GFRAL Antikörper (ABIN7874347) detektiert spezifisch GFRAL in WB, FACS und IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
GFRAL
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
25M22
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting points. Titration of the GFRAL antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the GFRAL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
GFRAL
(GDNF Family Receptor alpha Like (GFRAL))
Andere Bezeichnung
GFRAL
Hintergrund
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt]