Rekombinanter FOXP1 Antikörper (AA 350-450)
Kurzübersicht für Rekombinanter FOXP1 Antikörper (AA 350-450) (ABIN7874193)
Target
Alle FOXP1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 350-450
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Verwendungszweck
- FOXP1 Antibody / Forkhead box protein P1 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant fragment (within amino acids 350-450) of human FOXP1 protein was used as the immunogen for the FOXP1 antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the FOXP1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the FOXP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FOXP1 (Forkhead Box P1 (FOXP1))
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Andere Bezeichnung
- FOXP1
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Hintergrund
- Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff (~80 % +) for FOXP1 is needed to achieve high specificity for the ABC subtype.
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UniProt
- Q9H334
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Pathways
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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