LGI1 Antikörper (AA 35-557)

Produktnummer ABIN7874172

Der Kaninchen Polyklonal anti-LGI1 Antikörper wird verwendet zum Nachweis von LGI1 in Proben von Maus, Human und Ratte. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für LGI1 Antikörper (AA 35-557) (ABIN7874172)

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-LGI1 Antikörper

Bindungsspezifität: AA 35-557

Verwendungszweck: LGI1 Antibody / Leucine-rich glioma inactivated 1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids K35-A557) was used as the immunogen for the LGI1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LGI1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the LGI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Andere Bezeichnung: LGI1

Hintergrund: Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.

UniProt: O95970