RBP3 Antikörper (AA 333-1196)

Produktnummer ABIN7874030

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RBP3 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für RBP3 Antikörper (AA 333-1196) (ABIN7874030)

Target: RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-RBP3 Antikörper

Bindungsspezifität: AA 333-1196

Verwendungszweck: IRBP Antibody / RBP3 / Retinol-binding protein 3

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids L333-R1196) was used as the immunogen for the IRBP antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IRBP antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IRBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RBP3

Target: RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))

Andere Bezeichnung: IRBP

Hintergrund: Retinol-binding protein 3, interstitial (RBP3), also known as IRBP (Interphotoreceptor retinol-binding protein), is a protein that in humans is encoded by the RBP3 gene. Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process. The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38 % identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

UniProt: P10745