UBE2K Antikörper (AA 33-195)

Produktnummer ABIN7873990

Der Kaninchen Polyklonal anti-UBE2K Antikörper (ABIN7873990) detektiert spezifisch UBE2K in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für UBE2K Antikörper (AA 33-195) (ABIN7873990)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-UBE2K Antikörper

Bindungsspezifität: AA 33-195

Verwendungszweck: Huntingtin interacting protein 2 Antibody / HIP2 / UBE2K

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D33-E195) was used as the immunogen for the Huntingtin interacting protein 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Huntingtin interacting protein 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Huntingtin interacting protein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Andere Bezeichnung: Huntingtin interacting protein 2

Hintergrund: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

UniProt: P61086