SAP130 Antikörper (AA 309-913)

Produktnummer ABIN7873743

Der Kaninchen Polyklonal anti-SAP130 Antikörper wird verwendet zum Nachweis von SAP130 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC (p), IF und FACS.

Kurzübersicht für SAP130 Antikörper (AA 309-913) (ABIN7873743)

Target: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAP130 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-SAP130 Antikörper

Bindungsspezifität: AA 309-913

Verwendungszweck: SAP130 Antibody / Sin3-associated polypeptide p130

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids H309-H913) was used as the immunogen for the SAP130 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SAP130 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SAP130 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SAP130

Target: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Andere Bezeichnung: SAP130

Hintergrund: Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

UniProt: Q9H0E3