ENPP3 Antikörper (AA 300-600)

Produktnummer ABIN7873684

Der Maus Monoklonal anti-ENPP3 Antikörper (Klon ENPP3-9891) (ABIN7873684) detektiert spezifisch ENPP3 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ENPP3 Antikörper (AA 300-600) (ABIN7873684)

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ENPP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: ENPP3-9891

Produktdetails anti-ENPP3 Antikörper

Bindungsspezifität: AA 300-600

Verwendungszweck: PD-Ibeta Antibody / PDNP3 / ENPP3 / CD203c (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 300-600 from human ENPP3 protein was used as the immunogen for the PD-Ibeta antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PD-Ibeta antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PD-Ibeta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ENPP3

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Andere Bezeichnung: PD-Ibeta

Hintergrund: Ecto-nucleotide pyrophosphatase/phosphodiesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3 (PDNP3) which is also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. However, these allergies are not the only condition associated with CD203c upregulation, CD203c upregulation may also serve as a tumor marker for colon carcinoma.

UniProt: O14638

Pathways: Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity