Der Kaninchen Polyklonal anti-SAE1 Antikörper (ABIN7873600) detektiert spezifisch SAE1 in WB und IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
SAE1
Reaktivität: Human
ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting points. Titration of the SUMO-activating enzyme subunit 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the SUMO-activating enzyme subunit 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
SAE1
(SUMO1 Activating Enzyme Subunit 1 (SAE1))
Andere Bezeichnung
SUMO-activating enzyme subunit 1
Hintergrund
The dimeric enzyme AOS1 acts as a an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.